This was a case of a man from an endemic country with an encephalopathy of several weeks duration and a lumbar puncture with a lymphocytic pleocytosis, elevated protein, low glucose and no organisms on the LP. Viral PCR was also negative as were fungal studies. The presumed diagnosis on clinical grounds was TB meningitis.
A modern era review article including a discussion on the role of nuclear antigen testing is here.
The role of adjunctive dexamethasone in TB meningitis is described in an article from NEJM here.
There is a *great* free resource called the Canadian Tuberculosis Standards available here. This reference text provides a plethora of useful information on tuberculosis and would be a worthy addition to anyone's collection.
(I'm not providing you with medical advice. Clinical correlation and professional interpretation required)
Wednesday, January 28, 2009
Tuesday, January 13, 2009
Day #186 - PCP/HIV
I wasn't there (post-call) but I've blogged about this before and I encourage you to read that here.
Friday, January 9, 2009
Day #183 - Severe Influenza Redux
Previously presented this 'classic' case here.
Dr. Allison McGeer, the director of infection control and an infectious diseases physician here at MSH has recently published an article discussing the use of empiric influenza treatment in hospitalized patients here.
You can look up the current level of influenza across Canada here.
Dr. Allison McGeer, the director of infection control and an infectious diseases physician here at MSH has recently published an article discussing the use of empiric influenza treatment in hospitalized patients here.
You can look up the current level of influenza across Canada here.
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