This was a case of a man from an endemic country with an encephalopathy of several weeks duration and a lumbar puncture with a lymphocytic pleocytosis, elevated protein, low glucose and no organisms on the LP. Viral PCR was also negative as were fungal studies. The presumed diagnosis on clinical grounds was TB meningitis.
A modern era review article including a discussion on the role of nuclear antigen testing is here.
The role of adjunctive dexamethasone in TB meningitis is described in an article from NEJM here.
There is a *great* free resource called the Canadian Tuberculosis Standards available here. This reference text provides a plethora of useful information on tuberculosis and would be a worthy addition to anyone's collection.
No comments:
Post a Comment