Enterococcal Endocarditis

We saw a case of aortic and mitral valve enterococcal endocarditis.

Previous endocarditis blogs here with associated links.

While not really studied, there are some limited case reports or in vitro data for the possibility of:

• Daptomycin (also retrospective review in bacteremia here)
  
• Linezolid (and in general review of linezolid in IE here)
• Ceftobiprole (NB it lost its FDA approval in April 2010!)
  

Other options are reviewed here.

Though any of the above agents should primarily be used in the context of clinical trial or 'dire cicrumstances'